Douglas Powell

Douglas Powell

Company: Crown Bioscience

Job title: Director, Scientific Engagement


Leveraging PDX-derived Organoid (PDXO) Models for Combination Targeted Oncology 8:30 am

PDX-derived organoids are biologically equivalent to their matched PDX counterparts based on several shared characteristics Screening of PDXO in a combination matrix approach enables rapid and valuable insight into combination strategies A PDXO in vitro platform improves translatability of drug candidates, saves development time, and reduces animal usage by guiding optimal in vivo model selection…Read more

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