Speakers
Kimberly Aardalen
Scientific Technical Leader
Novartis Institutes for Biomedical Research
Dongfang Liu
Associate Professor & Director - Immunoassay Development Program
Rutgers New Jersey Medical School
Translation Track – Day 1 pm
1:50 pm | The Role of Immunological Synapse in Predicting the Efficacy of Chimeric Antigen Receptor (CAR) Immunotherapy
2:30 pm | Live Q&A
Brian Soper
Senior Technical Information Scientist
The Jackson Laboratory
Day One
Wednesday, July 14, 2021
4:40 pm | Panel Discussion: Organoids vs Humanized Mice - Modelling of the Tumor Landscape
Grace Berryhill
Senior Technical Information Scientist
The Jackson Laboratory
Day One
Wednesday, July 14, 2021
4:25 pm | Live Q&A - Ask Our Speakers Your Burning Questions
3:20 pm | New Humanized Mouse Models to Support NK Cell Research
Ganesh Mugundu
Head of Cell Therapy Clinical Pharmacology & Modelling
Takeda
Day Two
Thursday, July 15, 2021
3:40 pm | Chair’s Closing Remarks & End of Summit
3:20 pm | Live Q&A - Ask Our Speakers Your Burning Questions
3:00 pm | Clinical Dosing - Clinical Pharmacology & Modelling of Cell Therapies
12:00 pm | Live Q&A - Ask Our Speakers Your Burning Questions
8:45 am | Chair’s Opening Remarks
Rekha Pal
Director & Scientific Engagement
Crown Bioscience
Day One
Wednesday, July 14, 2021
4:40 pm | Panel Discussion: Organoids vs Humanized Mice - Modelling of the Tumor Landscape
10:20 am | Live Q&A - Ask Our Speakers Your Burning Questions
9:00 am | Translational Preclinical Platforms for CAR-T Cell Therapy
Aaron Goldman
Director, Drug Resistance Group
Harvard Medical School
Day Two
Thursday, July 15, 2021
9:30 am | Blending Tumor Models and Engineering to Accelerate Natural Killer Cell Therapies in Glioblastoma Multiformel
Jonathan Nakashima
Chief Scientific Officer
Certis Oncology Solutions
Day Two
Thursday, July 15, 2021
9:50 am | Orthotopic PDX Models Provide Relevant Tumor Microenvironments For Evaluating Cellular Therapies
Markus Vallaster
Senior Medical Director, Cell Therapies & Immuno-Oncology
AstraZeneca
Day Two
Thursday, July 15, 2021
3:20 pm | Live Q&A - Ask Our Speakers Your Burning Questions
2:20 pm | Translating Pre-Clinical Data into Innovative Clinical Trial Designs in Cell Therapies
Mari Kuraguchi
Director, in vivo Pharmacology, Principal Scientist
Biocytogen
Day Two
Thursday, July 15, 2021
9:00 am | Use of Humanized Mouse Models for Better Translation in Immunotherapy
Kris Richardson
Senior Data Scientist
Berg Health
Natasha Darras
Director, Cell Therapy Translational Medicine
Takeda Oncology
Translation Track - Day 1 am
12:10 pm | Live Q&A
11:10 am | Using Single-Cell Omics to Better Understand Tumor Complexity
Irena Adkins
Pharmacology & Science Lead
SOTIO
Day Two
Thursday, July 15, 2021
12:00 pm | Live Q&A - Ask Our Speakers Your Burning Questions
11:20 am | Understanding the Mechanistic Actions & Development of IL-15Rβγ Agonist
Shiva Kazerounian
Associate Director of in Vivo Pharmacology
Berg Health
Day Two
Thursday, July 15, 2021
1:20 pm | Panel: Diversity & Inclusion in Preclinical & Translational Studies
Translation Track - Day 1 am
12:10 pm | Live Q&A
11:30 am | Overcoming Cancer Drug Resistance
Simone Filosto
Principal Scientist, Translational Research & Clinical Pharmacology
Kite Pharma
Translation Track - Day 1 am
12:10 pm | Live Q&A
11:50 am | The Role of Translational Medicine in Supporting Product Developmen: An Axi-Cel Case Study
Chad May Senior
Vice President, Research & Development
Maverick Therapeutics
Day Two
Thursday, July 15, 2021
12:00 pm | Live Q&A - Ask Our Speakers Your Burning Questions
11:00 am | Conditionally Active COBRA T Cell Engagers Regress stablished Solid Tumors in Mice
Boris Engels
Associate Director
Novartis
Translation Track – Day 1 pm
2:30 pm | Live Q&A
1:30 pm | Assessing CAR-T Efficacy in Xenograft Models: Examples of Structure Activity Relationship
Principal Scientist
Bristol-Myers Squibb
Preclinical Track - Day 1 pm
2:05 pm | Live Q&A
1:45 pm | Microenvironment via Utilizing Human Tumor Ex Vivo Explant Model
Aman Singh
Associate Director, Clinical Pharmacology M&S
Takeda
Day Two
Thursday, July 15, 2021
3:20 pm | Live Q&A - Ask Our Speakers Your Burning Questions
2:00 pm | Bench to Bedside Translation of Chimeric Antigen Receptor (CAR) T Cells Using a Multiscale Systems PKPD Model
Joshua Breunig
Associate Professor
Cedars-Sinai Medical Centre
Day One
Wednesday, July 14, 2021
4:40 pm | Panel Discussion: Organoids vs Humanized Mice - Modelling of the Tumor Landscape
4:25 pm | Live Q&A - Ask Our Speakers Your Burning Questions
3:50 pm | Comparison of New Syngeneic Mouse Models & Human Organoids with Single Cell Sequencing
Viswanathan Muthusamy
Research Scientist, Executive Director
Yale School of Medicine
Day Two
Thursday, July 15, 2021
12:00 pm | Live Q&A - Ask Our Speakers Your Burning Questions
11:40 am | Novel Preclinical Models for Investigation of Immune Oncology Therapeutics
Eric Ibsen
Chief Executive Officer
Studylog
Anton Neschadim
Chief Executive Officer & Director
ImmunoBiochem Corp
Translation Track – Day 1 pm
2:30 pm | Live Q&A
2:10 pm | Relevant Humanized Models for the Evaluation of Efficacy and Safety of Targeted Innate Immunity Agonists for Immuno-Oncology
Yufei Wang
Research Fellow Dana-Faber
Cancer Institute
Day One
Wednesday, July 14, 2021
4:40 pm | Panel Discussion: Organoids vs Humanized Mice - Modelling of the Tumor Landscape
10:20 am | Live Q&A - Ask Our Speakers Your Burning Questions
9:30 am | Evaluate Immune Restoring CAR-T Cell Therapy on Clear Cell Renal Cell Carcinoma (ccRCC) Patient Derived Rrganotypic Spheroids (PDOTs) & Humanized Mouse Model
Kader Thiam
Senior Vice President Discovery - Preclinical Models & Services
GenOway
Day One
Wednesday, July 14, 2021
10:20 am | Live Q&A - Ask Our Speakers Your Burning Questions
9:50 am | Humanized Models Enabling Enhanced Clinical Relevancy & Translatability
Sheri Barnes
Associate Director - Scientific Development
Covance
Day One
Wednesday, July 14, 2021
4:10 pm | Generation of a CD19-CAR T Cell Therapy as a Tool for Preclinical Combination Strategies
4:25 pm | Live Q&A - Ask Our Speakers Your Burning Questions
Rakesh Awasthi
Clinical Pharmacology, Pharmacokinetic Oncology Sciences & Investigator
Novartis
Day Two
Thursday, July 15, 2021
3:20 pm | Live Q&A - Ask Our Speakers Your Burning Questions
2:40 pm | Clinical Pharmacology of Tisagenlecleucel in Adult Relapsed/ Refractory DLBCL Patients
Martina Molgora
Postdoctoral Researcher Washington
University School of Medicine
Preclinical Track - Day 1 am
12:05 pm | Live Q&A
11:45 am | Innate Immune Checkpoints in Tumor Immunotherapy
Nikolaus Krall
Chief Executive Officer & Co-founder
Allcyte
Preclinical Track - Day 1 am
12:05 pm | Live Q&A
11:30 am | Enabling Patient-Centric Cancer R&D with Primary Tissues & Pharmacoscopy®
John Maher
Senior Lecturer - Clinical Immunology
King’s College London