Enhancing Safety & Efficacy: sCD70-Armored CAR-T Cells
Time: 3:00 pm
day: Day 2 PM
Details:
- The study introduces a novel sCD70-armored CAR-T construct that improves CAR-T cell expansion, memory, ultimately enhancing antitumor efficacy
- This sCD70 CAR-T demonstrated superior in vivo performance with sustained cytotoxicity, and significant tumor control compared to unarmored CAR-T cells
- When compared to existing armor methods, this novel armor design shows potential to address safety concerns while maintaining robust antitumor efficacy
