09:00 - 17:30 EST | 6.00 - 14.30 PST

* Please note that the following agenda timings are Eastern Standard Time.  

For full agenda session details and Pacific Standard Times, please download the full event guide here

8:30 am Join Our Morning Coffee Chatroom to Get Started!

8:45 am Chair’s Opening Remarks

  • Ganesh Mugundu Head of Cell Therapy Clinical Pharmacology & Modelling, Takeda

Model Innovation for Cell Therapies

9:00 am Use of Humanized Mouse Models for Better Translation in Immunotherapy

  • Mari Kuraguchi Director, in vivo Pharmacology, Principal Scientist, Biocytogen

9:30 am Blending Tumor Models and Engineering to Accelerate Natural Killer Cell Therapies in Glioblastoma Multiformel

  • Aaron Goldman Director, Drug Resistance Group, Harvard Medical School

9:50 am Orthotopic PDX Models Provide Relevant Tumor Microenvironments For Evaluating Cellular Therapies

10:30 am Speed Networking

10:50 am Morning Networking Break & 1-2-1 Meetings

Assessing Tumor Regression, Metastasis & Mechanisms

11:00 am Conditionally Active COBRA T Cell Engagers Regress stablished Solid Tumors in Mice

  • Chad May Senior Vice President, Research & Development, Maverick Therapeutics

11:20 am Understanding the Mechanistic Actions & Development of IL-15Rβγ Agonist

11:40 am Novel Preclinical Models for Investigation of Immune Oncology Therapeutics

12:00 pm Live Q&A – Ask Our Speakers Your Burning Questions

12:20 pm Scientific Poster Session & Lunch Break

1:20 pm Panel: Diversity & Inclusion in Preclinical & Translational Studies

Guiding Clinical Design

2:00 pm Bench to Bedside Translation of Chimeric Antigen Receptor (CAR) T Cells Using a Multiscale Systems PKPD Model

  • Aman Singh Associate Director, Clinical Pharmacology M&S, Takeda

2:20 pm Translating Pre-Clinical Data into Innovative Clinical Trial Designs in Cell Therapies

  • Markus Vallaster Senior Medical Director, Cell Therapies & Immuno-Oncology, AstraZeneca

2:40 pm Clinical Pharmacology of Tisagenlecleucel in Adult Relapsed/ Refractory DLBCL Patients

  • Rakesh Awasthi Clinical Pharmacology, Pharmacokinetic Oncology Sciences & Investigator, Novartis

3:00 pm Clinical Dosing – Clinical Pharmacology & Modelling of Cell Therapies

  • Ganesh Mugundu Head of Cell Therapy Clinical Pharmacology & Modelling, Takeda

3:20 pm Live Q&A – Ask Our Speakers Your Burning Questions

  • Ganesh Mugundu Head of Cell Therapy Clinical Pharmacology & Modelling, Takeda
  • Markus Vallaster Senior Medical Director, Cell Therapies & Immuno-Oncology, AstraZeneca
  • Aman Singh Associate Director, Clinical Pharmacology M&S, Takeda
  • Rakesh Awasthi Clinical Pharmacology, Pharmacokinetic Oncology Sciences & Investigator, Novartis

3:40 pm Chair’s Closing Remarks & End of Summit

  • Ganesh Mugundu Head of Cell Therapy Clinical Pharmacology & Modelling, Takeda