Genetically Engineered Mouse Models to Empower Diffuse Large B Cell Lymphoma Therapeutic Improvement
Time: 2:00 pm
day: Day 1 Track A PM
Details:
- Whole exome sequencing in patients informs the generation of faithful mouse models to study DLBCL development and progression
- Single cell RNA sequencing allows to study B-cell lymphomagenesis and the concomitant T-cell-mediated immune response
- The combined analysis of asymptomatic animals at multiple time points and mice with lymphoma informs potential therapies for patients
