Pediatric Brain PDX Models for Preclinical Drug Development

Time: 11:30 am
day: Applications in Drug Delivery & Screening Day 2 AM


  • Feasibility and robustness of a tumor-tracking optical imaging system in PDX models  
  • Single mouse trial as a screening tool to characterize PDX cohorts and identify the most efficacious compounds in vivo to overcome the lack of clinical trials for pediatric cancer
  • Preclinical validation set, including molecular characterization of donor patient and PDX